TMPRSS2 and TMEM11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMPRSS2	TMEM11
Description		transmembrane serine protease 2	transmembrane protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Mitochondrion Integral Component Of Plasma Membrane Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Molecular_function Protein Binding
	Biological Process	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell	Mitochondrion Organization Inner Mitochondrial Membrane Organization
Pathways		Attachment and Entry Attachment and Entry Attachment and Entry	Cristae formation
Drugs		Camostat
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Prostate cancer ( 25217961)	Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		60 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF TRAPPC10 UPK2 VAMP5 ZFPL1	54 interacting genes: ARL13B BDKRB2 BIK BNIP3 BNIP3L CCDC70 CCR4 CD200 CD79A CLDN7 CLN8 CREB3L1 CYB561 CYB5D2 DRD2 EBP ELOVL4 FAM174A FAM209A FAM210B FATE1 FFAR2 GJB4 GORAB KASH5 LEPROTL1 LMNA MRM1 MSMO1 MTIF3 MUC1 NDUFS3 OTX2 PDZK1IP1 PEX12 RETREG3 RIC3 RNASEH1 SCMH1 SGCB SLC10A6 SLC30A8 SUSD3 SUV39H1 TEX29 TMEM106C TMEM14B TMEM205 TMEM237 TMEM88 TMIE TMPRSS2 TNFSF14 YIPF6
Entrez ID		7113	8834
HPRD ID		03637	12680
Ensembl ID		ENSG00000184012	ENSG00000178307
Uniprot IDs		O15393	P17152
PDB IDs
Enriched GO Terms of Interacting Partners?
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