TMPRSS2 and MOSPD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMPRSS2	MOSPD3
Description		transmembrane serine protease 2	motile sperm domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Protein Binding FFAT Motif Binding
	Biological Process	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell	Heart Development Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Membrane Organization
Pathways		Attachment and Entry Attachment and Entry Attachment and Entry
Drugs		Camostat
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Prostate cancer ( 25217961)	High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 28017375) Mean reticulocyte volume ( 32888494) Red blood cell count ( 28453575)
Interacting Genes		60 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF TRAPPC10 UPK2 VAMP5 ZFPL1	17 interacting genes: ARL13B ATP5PF CD79A FATE1 FNDC9 GPR152 HSD17B13 IER3IP1 KASH5 MFF MILR1 PSCA REEP4 RETREG3 RILPL1 SAR1A TMPRSS2
Entrez ID		7113	64598
HPRD ID		03637	12370
Ensembl ID		ENSG00000184012	ENSG00000106330
Uniprot IDs		O15393	O75425
PDB IDs
Enriched GO Terms of Interacting Partners?
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