TMPRSS2 and C1QL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMPRSS2	C1QL4
Description		transmembrane serine protease 2	complement C1q like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Collagen Trimer Extracellular Space
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Protein Binding Identical Protein Binding
	Biological Process	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell	Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Fibroblast Proliferation Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Attachment and Entry Attachment and Entry Attachment and Entry
Drugs		Camostat
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Prostate cancer ( 25217961)
Interacting Genes		60 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF TRAPPC10 UPK2 VAMP5 ZFPL1	19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2
Entrez ID		7113	338761
HPRD ID		03637	17350
Ensembl ID		ENSG00000184012	ENSG00000186897
Uniprot IDs		O15393	A0A3B0INP7 Q86Z23
PDB IDs
Enriched GO Terms of Interacting Partners?
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