MPP1 and SGSM2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPP1	SGSM2
Gene Name		membrane protein, palmitoylated 1, 55kDa	small G protein signaling modulator 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium
	Molecular Function	Guanylate Kinase Activity Protein Binding	Rab GTPase Activator Activity Rab GTPase Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation Regulation Of Neutrophil Chemotaxis	Positive Regulation Of Rab GTPase Activity Late Endosome To Golgi Transport
Pathways
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Aortic root size ( 19584346) Proinsulin levels ( 21873549)
Protein-Protein Interactions		19 interactors: AMOTL2 ATP5C1 DNPEP ERBB2IP GADD45A GSK3B GYPC HNRNPD KLHL12 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 STK3 STUB1 TK1 ZAK	14 interactors: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 PNO1 PTN RGMA RPS25
Entrez ID		4354	9905
HPRD ID		02370	15284
Ensembl ID		ENSG00000130830	ENSG00000141258
Uniprot IDs		B4E325 Q00013	B9A6J3 O43147
PDB IDs		2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Communication Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Phosphorylation Intracellular Signal Transduction Regulation Of JNK Cascade Positive Regulation Of Cellular Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stimulus Intracellular Transport Positive Regulation Of Transferase Activity Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Fetal Process Involved In Parturition Negative Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Binding Golgi Vesicle Transport Positive Regulation Of Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway
Tagcloud ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously
Tagcloud (Difference) ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously
Tagcloud (Intersection) ?