SGSM2 and CA12

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SGSM2	CA12
Gene Name		small G protein signaling modulator 2	carbonic anhydrase XII
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Integral Component Of Membrane
	Molecular Function	Rab GTPase Activator Activity Rab GTPase Binding	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Late Endosome To Golgi Transport	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process Chloride Ion Homeostasis
Pathways			Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Zonisamide Hydrochlorothiazide Ellagic Acid
Diseases
GWAS		Aortic root size ( 19584346) Proinsulin levels ( 21873549)
Protein-Protein Interactions		14 interactors: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 PNO1 PTN RGMA RPS25	10 interactors: ATP5C1 CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1
Entrez ID		9905	771
HPRD ID		15284	04464
Ensembl ID		ENSG00000141258
Uniprot IDs		B9A6J3 O43147	B3KUB4 O43570
PDB IDs			1JCZ 1JD0 4HT2
Enriched GO Terms of Interacting Partners?
Tagcloud ?			adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman
Tagcloud (Difference) ?			adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman
Tagcloud (Intersection) ?