SGSM2 and FNBP1L

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SGSM2	FNBP1L
Gene Name		small G protein signaling modulator 2	formin binding protein 1-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Rab GTPase Binding	Protein Binding Lipid Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Late Endosome To Golgi Transport	Membrane Budding Autophagy Membrane Invagination Vesicle Organization Vesicle Transport Along Actin Filament Cilium Assembly Positive Regulation Of Filopodium Assembly Clathrin-mediated Endocytosis Membrane Tubulation
Pathways
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Proinsulin levels ( 21873549)
Protein-Protein Interactions		14 interactors: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 PNO1 PTN RGMA RPS25	5 interactors: ACP1 DNM2 SGSM2 USP13 WASL
Entrez ID		9905	54874
HPRD ID		15284	12317
Ensembl ID		ENSG00000141258	ENSG00000137942
Uniprot IDs		B9A6J3 O43147	B4DSI7 J3QSS4 Q5T0N5
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Membrane Tubulation Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Nitric-oxide Synthase Activity Regulation Of Oxidoreductase Activity Reactive Oxygen Species Metabolic Process Vesicle Transport Along Actin Filament Late Endosome To Golgi Transport Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Clathrin-mediated Endocytosis Golgi Vesicle Transport Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Establishment Of Organelle Localization Vesicle-mediated Transport Regulation Of Clathrin-mediated Endocytosis Organelle Localization Cellular Protein Complex Localization Protein K63-linked Deubiquitination Regulation Of Cell Projection Organization Protein Complex Localization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
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