MPP1 and STK3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MPP1	STK3
Gene Name		membrane protein, palmitoylated 1, 55kDa	serine/threonine kinase 3
Image
Gene Ontology Annotations	Cellular Component	Intracellular Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium	Nucleus Cytoplasm Cytosol
	Molecular Function	Guanylate Kinase Activity Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine/threonine Kinase Activator Activity Protein Dimerization Activity
	Biological Process	Signal Transduction Nucleotide Phosphorylation Regulation Of Neutrophil Chemotaxis	Neural Tube Formation Endocardium Development Protein Phosphorylation Apoptotic Process Signal Transduction Central Nervous System Development Negative Regulation Of Cell Proliferation Signal Transduction By Phosphorylation Positive Regulation Of Protein Binding Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of Organ Growth Protein Stabilization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Primitive Hemopoiesis Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Hepatocyte Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Protein-Protein Interactions		19 interactors: AMOTL2 ATP5C1 DNPEP ERBB2IP GADD45A GSK3B GYPC HNRNPD KLHL12 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 STK3 STUB1 TK1 ZAK	33 interactors: AKT1 CASP3 CNKSR1 CPNE1 DDAH2 EIF4EBP1 FAM9B GAD1 GBP2 GMCL1 HSPE1 KHSRP LATS1 LATS2 LRRK2 MBP MOB4 MPP1 ORM2 PEX19 PHAX QARS RAF1 RASSF1 RASSF2 RASSF4 RASSF5 SAV1 SLMAP SULT2A1 TFPT TRAF1 ZC3H7A
Entrez ID		4354	6788
HPRD ID		02370	05433
Ensembl ID		ENSG00000130830	ENSG00000104375
Uniprot IDs		B4E325 Q00013	B3KYA7 Q13188
PDB IDs		2EJY 2EV8 3NEY	4HKD 4L0N 4LG4 4LGD
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Communication Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Phosphorylation Intracellular Signal Transduction Regulation Of JNK Cascade Positive Regulation Of Cellular Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stimulus Intracellular Transport Positive Regulation Of Transferase Activity Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Fetal Process Involved In Parturition Negative Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Binding Golgi Vesicle Transport Positive Regulation Of Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway	Hippo Signaling Intracellular Signal Transduction Response To Stimulus Signaling Cell Communication Keratinocyte Differentiation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Metabolic Process Signal Transduction Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Epidermal Cell Differentiation Cell Death Death Negative Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Nitric Oxide Biosynthetic Process Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Organic Substance Skin Development Negative Regulation Of Kinase Activity Programmed Cell Death Posttranscriptional Regulation Of Gene Expression Regulation Of Protein Kinase Activity Mitotic Cell Cycle Phase Transition Regulation Of Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Epidermis Development Cellular Response To Organic Substance Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Reactive Oxygen Species Metabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Epithelial Cell Differentiation Negative Regulation Of Oxidative Stress-induced Cell Death
Tagcloud ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Difference) ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Intersection) ?