SGSM2 and CELSR3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SGSM2	CELSR3
Gene Name		small G protein signaling modulator 2	cadherin, EGF LAG seven-pass G-type receptor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Integral Component Of Membrane
	Molecular Function	Rab GTPase Activator Activity Rab GTPase Binding	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Late Endosome To Golgi Transport	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Proinsulin levels ( 21873549)
Protein-Protein Interactions		14 interactors: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 PNO1 PTN RGMA RPS25	11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		9905	1951
HPRD ID		15284	09179
Ensembl ID		ENSG00000141258	ENSG00000008300
Uniprot IDs		B9A6J3 O43147	Q9NYQ7
PDB IDs
Enriched GO Terms of Interacting Partners?			Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution
Tagcloud ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?