Search Results for: PTEN

365 interactions involving PTEN - phosphatase and tensin homolog found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DDX1 DEAD-box helicase 1
  • tRNA processing in the nucleus
DDX21 DExD-box helicase 21
  • B-WICH complex positively regulates rRNA expression
  • Major pathway of rRNA processing in the nucleolus and cytosol
DDX24 DEAD-box helicase 24
DDX47 DEAD-box helicase 47
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
DDX50 DExD-box helicase 50
DHX15 DEAH-box helicase 15
  • mRNA Splicing - Major Pathway
DHX9 DExH-box helicase 9
  • RIP-mediated NFkB activation via ZBP1
  • DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • mRNA Splicing - Major Pathway
DLC1 DLC1 Rho GTPase activating protein
  • Rho GTPase cycle
DLG1 discs large MAGUK scaffold protein 1
  • Trafficking of AMPA receptors
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • NrCAM interactions
  • Activation of Ca-permeable Kainate Receptor
  • RAF/MAP kinase cascade
  • Synaptic adhesion-like molecules
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
DNAJA1 DnaJ heat shock protein family (Hsp40) member A1
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
DNAJA2 DnaJ heat shock protein family (Hsp40) member A2
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
DNAJA3 DnaJ heat shock protein family (Hsp40) member A3
DNAJB6 DnaJ heat shock protein family (Hsp40) member B6
  • Regulation of HSF1-mediated heat shock response
DNAJC10 DnaJ heat shock protein family (Hsp40) member C10
DPM1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic
  • Synthesis of dolichyl-phosphate mannose
  • Defective DPM1 causes DPM1-CDG (CDG-1e)
  • Defective DPM3 causes DPM3-CDG (CDG-1o)
  • Defective DPM2 causes DPM2-CDG (CDG-1u)
  • Congenital disorders of glycosylation (CDG) type I
DRG1 developmentally regulated GTP binding protein 1
EXOSC1 exosome component 1
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC2 exosome component 2
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC4 exosome component 4
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC5 exosome component 5
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol

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