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CCT4 |
chaperonin containing TCP1 subunit 4 |
- Prefoldin mediated transfer of substrate to CCT/TriC
- Formation of tubulin folding intermediates by CCT/TriC
- Folding of actin by CCT/TriC
- Association of TriC/CCT with target proteins during biosynthesis
- Association of TriC/CCT with target proteins during biosynthesis
- BBSome-mediated cargo-targeting to cilium
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
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CCT6A |
chaperonin containing TCP1 subunit 6A |
- Prefoldin mediated transfer of substrate to CCT/TriC
- Formation of tubulin folding intermediates by CCT/TriC
- Folding of actin by CCT/TriC
- Association of TriC/CCT with target proteins during biosynthesis
- Association of TriC/CCT with target proteins during biosynthesis
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
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CCT8 |
chaperonin containing TCP1 subunit 8 |
- Prefoldin mediated transfer of substrate to CCT/TriC
- Formation of tubulin folding intermediates by CCT/TriC
- Folding of actin by CCT/TriC
- Association of TriC/CCT with target proteins during biosynthesis
- Association of TriC/CCT with target proteins during biosynthesis
- BBSome-mediated cargo-targeting to cilium
- Neutrophil degranulation
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
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CDC27 |
cell division cycle 27 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
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CEP170 |
centrosomal protein 170 |
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CEP97 |
centrosomal protein 97 |
- Anchoring of the basal body to the plasma membrane
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CHD4 |
chromodomain helicase DNA binding protein 4 |
- HDACs deacetylate histones
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- Regulation of TP53 Activity through Acetylation
- RNA Polymerase I Transcription Initiation
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- NGF-stimulated transcription
- Potential therapeutics for SARS
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CHGB |
chromogranin B |
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
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COPA |
COPI coat complex subunit alpha |
- COPI-mediated anterograde transport
- COPI-dependent Golgi-to-ER retrograde traffic
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COPB1 |
COPI coat complex subunit beta 1 |
- Neutrophil degranulation
- COPI-mediated anterograde transport
- COPI-dependent Golgi-to-ER retrograde traffic
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COPS6 |
COP9 signalosome subunit 6 |
- DNA Damage Recognition in GG-NER
- Formation of TC-NER Pre-Incision Complex
- Cargo recognition for clathrin-mediated endocytosis
- Neddylation
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CUL4B |
cullin 4B |
- Recognition of DNA damage by PCNA-containing replication complex
- DNA Damage Recognition in GG-NER
- Formation of Incision Complex in GG-NER
- Dual Incision in GG-NER
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Neddylation
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- Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
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CXCL1 |
C-X-C motif chemokine ligand 1 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
- Interleukin-10 signaling
- Neutrophil degranulation
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DAP3 |
death associated protein 3 |
- Mitochondrial translation initiation
- Mitochondrial translation elongation
- Mitochondrial translation elongation
- Mitochondrial translation termination
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DAXX |
death domain associated protein |
- SUMOylation of transcription cofactors
- Regulation of TP53 Degradation
- HCMV Early Events
- Inhibition of DNA recombination at telomere
- Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations
- Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations
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DBN1 |
drebrin 1 |
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DCAF11 |
DDB1 and CUL4 associated factor 11 |
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DCAF13 |
DDB1 and CUL4 associated factor 13 |
- rRNA modification in the nucleus and cytosol
- Major pathway of rRNA processing in the nucleolus and cytosol
- Neddylation
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DDB1 |
damage specific DNA binding protein 1 |
- Recognition of DNA damage by PCNA-containing replication complex
- DNA Damage Recognition in GG-NER
- Formation of Incision Complex in GG-NER
- Dual Incision in GG-NER
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Neddylation
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- Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
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DDOST |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
- SRP-dependent cotranslational protein targeting to membrane
- Asparagine N-linked glycosylation
- Neutrophil degranulation
- Advanced glycosylation endproduct receptor signaling
- Maturation of spike protein
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