PTEN - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide
IL24	interleukin 24	Interleukin-20 family signaling
ILF2	interleukin enhancer binding factor 2	Neutrophil degranulation
ILF3	interleukin enhancer binding factor 3
IPO5	importin 5	vRNP Assembly
IPO7	importin 7
IRS4	insulin receptor substrate 4	IRS-related events triggered by IGF1R
ITPRID2	ITPR interacting domain containing 2
KBTBD4	kelch repeat and BTB domain containing 4
KDM1A	lysine demethylase 1A	HDACs deacetylate histones HDMs demethylate histones Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Regulation of PTEN gene transcription Estrogen-dependent gene expression NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
KPNB1	karyopherin subunit beta 1	ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Regulation of cholesterol biosynthesis by SREBP (SREBF) Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Nuclear import of Rev protein Nuclear import of Rev protein Initiation of Nuclear Envelope (NE) Reformation Neutrophil degranulation Postmitotic nuclear pore complex (NPC) reformation Inhibition of nitric oxide production
LIMA1	LIM domain and actin binding 1
LINC00839	long intergenic non-protein coding RNA 839
LINC01198	long intergenic non-protein coding RNA 1198
LINC02023	long intergenic non-protein coding RNA 2023
LMNB1	lamin B1	Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
LRPPRC	leucine rich pentatricopeptide repeat containing	TP53 Regulates Metabolic Genes Respiratory electron transport
LTV1	LTV1 ribosome biogenesis factor	Major pathway of rRNA processing in the nucleolus and cytosol
MAGED2	MAGE family member D2	Platelet degranulation
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	Nephrin family interactions
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3

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