Search Results for: ATXN1

292 interactions involving ATXN1 - ataxin 1 found:

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MBP myelin basic protein
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
MED15 mediator complex subunit 15
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
METTL17 methyltransferase like 17
METTL27 methyltransferase like 27
MLST8 MTOR associated protein, LST8 homolog
  • PIP3 activates AKT signaling
  • Macroautophagy
  • MTOR signalling
  • mTORC1-mediated signalling
  • HSF1-dependent transactivation
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • CD28 dependent PI3K/Akt signaling
  • VEGFR2 mediated vascular permeability
  • TP53 Regulates Metabolic Genes
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Regulation of TP53 Degradation
  • Regulation of PTEN gene transcription
  • Amino acids regulate mTORC1
MSX2 msh homeobox 2
  • Regulation of RUNX2 expression and activity
  • Enlarged parietal foramina/cranium bifidum
  • Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
MTERF4 mitochondrial transcription termination factor 4
  • rRNA modification in the mitochondrion
MYO18A myosin XVIIIA
  • Signaling by cytosolic FGFR1 fusion mutants
  • Signaling by FGFR1 in disease
  • Signaling by FLT3 fusion proteins
  • Signaling by FLT3 fusion proteins
NCAM1 neural cell adhesion molecule 1
  • ECM proteoglycans
  • NCAM signaling for neurite out-growth
  • NCAM signaling for neurite out-growth
  • NCAM1 interactions
  • NCAM1 interactions
  • Signal transduction by L1
  • RAF/MAP kinase cascade
  • Interferon gamma signaling
NCOR1 nuclear receptor corepressor 1
  • Nuclear signaling by ERBB4
  • Nuclear signaling by ERBB4
  • NR1D1 (REV-ERBA) represses gene expression
  • PPARA activates gene expression
  • PPARA activates gene expression
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Transcriptional activation of mitochondrial biogenesis
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HDACs deacetylate histones
  • Notch-HLH transcription pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Nuclear Receptor transcription pathway
  • Regulation of lipid metabolism by PPARalpha
  • Circadian Clock
  • Circadian Clock
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Loss of MECP2 binding ability to the NCoR/SMRT complex
  • Regulation of MECP2 expression and activity
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • HCMV Early Events
  • NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
NCOR2 nuclear receptor corepressor 2
  • PPARA activates gene expression
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HDACs deacetylate histones
  • Notch-HLH transcription pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Nuclear Receptor transcription pathway
  • SUMOylation of transcription cofactors
  • Regulation of lipid metabolism by PPARalpha
  • Loss of MECP2 binding ability to the NCoR/SMRT complex
  • Regulation of MECP2 expression and activity
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • HCMV Early Events
  • NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
NFYA nuclear transcription factor Y subunit alpha
  • PPARA activates gene expression
  • Activation of gene expression by SREBF (SREBP)
  • Activation of gene expression by SREBF (SREBP)
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • ATF6 (ATF6-alpha) activates chaperone genes
  • ATF6 (ATF6-alpha) activates chaperone genes
  • FOXO-mediated transcription of cell death genes
NHSL2 NHS like 2
NLK nemo like kinase
  • Ca2+ pathway
NPHP3 nephrocystin 3
  • Trafficking of myristoylated proteins to the cilium
  • Senior-Loken syndrome
  • Renal-hepatic-pancreatic dysplasia
  • Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
  • Meckel syndrome (MKS); Meckel-Gruber syndrome
NR4A1 nuclear receptor subfamily 4 group A member 1
  • AKT phosphorylates targets in the nucleus
  • Nuclear Receptor transcription pathway
  • Constitutive Signaling by AKT1 E17K in Cancer
NUDT21 nudix hydrolase 21
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
NUMBL NUMB like endocytic adaptor protein
NUTM2B NUT family member 2B
OPCML opioid binding protein/cell adhesion molecule like
  • Post-translational modification: synthesis of GPI-anchored proteins

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