Search Results for: ATXN1

292 interactions involving ATXN1 - ataxin 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CRIP2 cysteine rich protein 2
CRK CRK proto-oncogene, adaptor protein
  • ARMS-mediated activation
  • ARMS-mediated activation
  • Downstream signal transduction
  • Regulation of actin dynamics for phagocytic cup formation
  • p130Cas linkage to MAPK signaling for integrins
  • VEGFA-VEGFR2 Pathway
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • MET activates RAP1 and RAC1
  • MET receptor recycling
  • Regulation of signaling by CBL
  • FCGR3A-mediated phagocytosis
CRX cone-rod homeobox
  • Leber congenital amaurosis (LCR)
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
CRY2 cryptochrome circadian regulator 2
  • Circadian Clock
CST3 cystatin C
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Neutrophil degranulation
  • Post-translational protein phosphorylation
  • Amyloid fiber formation
  • Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
CUTC cutC copper transporter
  • Ion transport by P-type ATPases
DAZ2 deleted in azoospermia 2
DAZAP2 DAZ associated protein 2
DCTN3 dynactin subunit 3
  • MHC class II antigen presentation
  • Regulation of PLK1 Activity at G2/M Transition
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • AURKA Activation by TPX2
DHRSX dehydrogenase/reductase X-linked
DHX37 DEAH-box helicase 37
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
DIXDC1 DIX domain containing 1
DNAJA3 DnaJ heat shock protein family (Hsp40) member A3
DOCK5 dedicator of cytokinesis 5
  • Factors involved in megakaryocyte development and platelet production
DZIP3 DAZ interacting zinc finger protein 3
  • Antigen processing: Ubiquitination & Proteasome degradation
EFEMP2 EGF containing fibulin extracellular matrix protein 2
  • Molecules associated with elastic fibres
  • Molecules associated with elastic fibres
  • Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
EHMT1 euchromatic histone lysine methyltransferase 1
  • Senescence-Associated Secretory Phenotype (SASP)
  • PKMTs methylate histone lysines
  • Regulation of TP53 Activity through Methylation
  • Transcriptional Regulation by VENTX
  • Transcriptional Regulation by E2F6
  • Kleefstra syndrome; 9q Subtelomeric deletion syndrome
EIF1AY eukaryotic translation initiation factor 1A Y-linked
EIF1B eukaryotic translation initiation factor 1B
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1

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