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PSMC3 |
proteasome 26S subunit, ATPase 3 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- Neutrophil degranulation
- CDT1 association with the CDC6:ORC:origin complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
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PTGDS |
prostaglandin D2 synthase |
- Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
- Transcriptional regulation of testis differentiation
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SF1 |
splicing factor 1 |
- mRNA Splicing - Major Pathway
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SLC6A13 |
solute carrier family 6 member 13 |
- Na+/Cl- dependent neurotransmitter transporters
- Reuptake of GABA
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YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Deactivation of the beta-catenin transactivating complex
- Rap1 signalling
- GP1b-IX-V activation signalling
- KSRP (KHSRP) binds and destabilizes mRNA
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- NOTCH4 Activation and Transmission of Signal to the Nucleus
- Negative regulation of NOTCH4 signaling
- Regulation of localization of FOXO transcription factors
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ZYX |
zyxin |
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uncharacterized LOC401442 |
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ACOT7 |
acyl-CoA thioesterase 7 |
- Mitochondrial Fatty Acid Beta-Oxidation
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ADAM15 |
ADAM metallopeptidase domain 15 |
- Degradation of the extracellular matrix
- Invadopodia formation
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ADCY6 |
adenylate cyclase 6 |
- Glucagon signaling in metabolic regulation
- PKA activation
- PKA activation in glucagon signalling
- Adenylate cyclase activating pathway
- Adenylate cyclase inhibitory pathway
- Adenylate cyclase inhibitory pathway
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- G alpha (s) signalling events
- G alpha (s) signalling events
- G alpha (i) signalling events
- G alpha (z) signalling events
- G alpha (z) signalling events
- Vasopressin regulates renal water homeostasis via Aquaporins
- Hedgehog 'off' state
- ADORA2B mediated anti-inflammatory cytokines production
- ADORA2B mediated anti-inflammatory cytokines production
- FCGR3A-mediated IL10 synthesis
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ADD3 |
adducin 3 |
- Miscellaneous transport and binding events
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AHDC1 |
AT-hook DNA binding motif containing 1 |
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ANKHD1 |
ankyrin repeat and KH domain containing 1 |
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ANP32A |
acidic nuclear phosphoprotein 32 family member A |
- HuR (ELAVL1) binds and stabilizes mRNA
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APBB1 |
amyloid beta precursor protein binding family B member 1 |
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
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ARHGAP32 |
Rho GTPase activating protein 32 |
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ARID5A |
AT-rich interaction domain 5A |
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ATXN1L |
ataxin 1 like |
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ATXN2 |
ataxin 2 |
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- Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
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ATXN2L |
ataxin 2 like |
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