PEA15 and CEP120

Data Source:
BioGRID (two hybrid)

		PEA15	CEP120
Description		proliferation and apoptosis adaptor protein 15	centrosomal protein 120
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Cytoplasm Centrosome Centriole
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Centrosome Cycle Positive Regulation Of Centrosome Duplication Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Astral Microtubule Organization Positive Regulation Of Cilium Assembly Positive Regulation Of Centriole Elongation Positive Regulation Of Establishment Of Protein Localization
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 28892062) Coronary artery disease ( 29212778) Height ( 20881960 25429064 31562340) Multisite chronic pain ( 31194737) Obesity (extreme) ( 30677029) Pulse pressure ( 30578418) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference ( 26785701)
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	2 interacting genes: PEA15 STAT3
Entrez ID		8682	153241
HPRD ID		04579	08769
Ensembl ID		ENSG00000162734	ENSG00000168944
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	B4DLH5 Q8N960
PDB IDs		4IZ5 4IZA 6P6B 6P6C	4ICW 4ICX 6FLJ 6FLK
Enriched GO Terms of Interacting Partners?
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