PEA15 and SON

Data Source:
BioGRID (two hybrid)

		PEA15	SON
Description		proliferation and apoptosis adaptor protein 15	SON DNA and RNA binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Nuclear Speck
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Microtubule Cytoskeleton Organization Mitotic Cytokinesis MRNA Processing RNA Splicing Negative Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS			Psoriasis ( 25854761)
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	10 interacting genes: CLIP4 MAGEA6 PEA15 PRPF40A SNIP1 SRPK2 TRIP6 VHL YWHAB YWHAG
Entrez ID		8682	6651
HPRD ID		04579	01678
Ensembl ID		ENSG00000162734	ENSG00000159140
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	J3QSZ5 P18583 Q6ZRV7
PDB IDs		4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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