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SYVN1 and GPR37
Data Source:
BioGRID
(enzymatic study)
SYVN1
GPR37
Description
synoviolin 1
G protein-coupled receptor 37
Image
No pdb structure
GO Annotations
Cellular Component
Hrd1p Ubiquitin Ligase Complex
Hrd1p Ubiquitin Ligase ERAD-L Complex
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Ubiquitin Ligase Complex
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Receptor Complex
Molecular Function
Protein Binding
Metal Ion Binding
Unfolded Protein Binding
Chaperone Binding
ATPase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-specific Protease Binding
G Protein-coupled Receptor Activity
Protein Binding
Neuropeptide Receptor Activity
G Protein-coupled Peptide Receptor Activity
Hsp70 Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Prosaposin Receptor Activity
Peptide Binding
Neuropeptide Binding
Biological Process
Immature B Cell Differentiation
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Retrograde Protein Transport, ER To Cytosol
IRE1-mediated Unfolded Protein Response
ERAD Pathway
Protein Stabilization
Protein K48-linked Ubiquitination
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Endoplasmic Reticulum Mannose Trimming
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Locomotion Involved In Locomotory Behavior
Dopamine Biosynthetic Process
Positive Regulation Of MAPK Cascade
Positive Regulation Of Dopamine Metabolic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways
XBP1(S) activates chaperone genes
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
ER Quality Control Compartment (ERQC)
Peptide ligand-binding receptors
G alpha (i) signalling events
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Crohn's disease (
32581322
)
Ankylosing spondylitis (
23749187
)
Cutaneous malignant melanoma (
32341527
26237428
)
Nevus count or cutaneous melanoma (
32341527
)
Reading and spelling (
23738518
)
Refractive error (
32231278
)
Interacting Genes
13 interacting genes:
APP
ATN1
CLU
ERN1
GPR37
TP53
UBE2D2
UBE2D3
UBE2G1
UBE2U
UBE2Z
USP15
USP7
51 interacting genes:
ADGRB1
ADORA2A
ADRA1A
ADRB2
BNIP3
CCNQ
CNTN1
DRD2
ERGIC3
FA2H
FKBP8
FUCA2
G6PC3
GABARAPL2
GABBR1
GHITM
GLP1R
GPR17
GRIP1
HDGF
HLA-C
HSP90B1
HSPA1A
HTR2C
HTR4
IFITM3
JKAMP
LTB4R2
P4HTM
PPM1J
PRKN
SDCBP
SLC37A1
SLC3A2
SLC41A3
SLC8A2
SPATA2L
STUB1
SYVN1
TAFA5
TMED1
TMEM161A
TMEM175
TMEM231
TMEM63A
TTYH1
TTYH2
WLS
YIF1A
YIF1B
ZDHHC11
Entrez ID
84447
2861
HPRD ID
07618
03992
Ensembl ID
ENSG00000162298
ENSG00000170775
Uniprot IDs
Q86TM6
O15354
PDB IDs
6A3Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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