GPR37 and FUCA2

Data Source:
BioGRID (two hybrid)

		GPR37	FUCA2
Description		G protein-coupled receptor 37	alpha-L-fucosidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding	Alpha-L-fucosidase Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 32341527 26237428) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)	Multiple sclerosis ( 31604244)
Interacting Genes		51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11	18 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 PIN1 TNPO2 VWC2 WNT11
Entrez ID		2861	2519
HPRD ID		03992	00649
Ensembl ID		ENSG00000170775	ENSG00000001036
Uniprot IDs		O15354	Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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