GPR37 and SLC3A2

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		GPR37	SLC3A2
Description		G protein-coupled receptor 37	solute carrier family 3 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Nucleoplasm Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cell Junction Melanosome Extracellular Exosome Amino Acid Transport Complex
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding	RNA Binding Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Cadherin Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Phenylalanine Transport Tryptophan Transport Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Leucine Import Across Plasma Membrane L-alpha-amino Acid Transmembrane Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 32341527 26237428) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)	Iron status biomarkers (transferrin saturation) ( 28334935)
Interacting Genes		51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11	16 interacting genes: CCR4 EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL
Entrez ID		2861	6520
HPRD ID		03992	01148
Ensembl ID		ENSG00000170775	ENSG00000168003
Uniprot IDs		O15354	J3KPF3 P08195
PDB IDs			2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V
Enriched GO Terms of Interacting Partners?
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