GPR37 and G6PC3

Data Source:
BioGRID (two hybrid)

		GPR37	G6PC3
Description		G protein-coupled receptor 37	glucose-6-phosphatase catalytic subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding	Glucose-6-phosphatase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Gluconeogenesis Glucose-6-phosphate Transport Dephosphorylation Glucose 6-phosphate Metabolic Process
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Severe congenital neutropenia type 4 (G6PC3) Gluconeogenesis
Drugs
Diseases			Neutropenia, severe congenital 4, autosomal recessive; G6PC3 deficiency; Darsun syndrome
GWAS		Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 32341527 26237428) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)	Bipolar disorder ( 31043756) Glycated hemoglobin levels ( 24244560)
Interacting Genes		51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11	3 interacting genes: CCR9 GPR37 HTR2B
Entrez ID		2861	92579
HPRD ID		03992	13556
Ensembl ID		ENSG00000170775	ENSG00000141349
Uniprot IDs		O15354	Q9BUM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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