TMEM222 and PRSS23

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TMEM222	PRSS23
Description		transmembrane protein 222	serine protease 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process		Proteolysis Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 31219225)	Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		38 interacting genes: ABHD16A AQP6 BIK BSCL2 CD79A CLDN5 CLRN1 COMT CRB3 CREB3 CREB3L1 EBP ELOVL4 ERG28 ERGIC3 EVI2B FAM174A FAM209A HIBADH HSD17B13 KIR2DL3 LMNA LRRC59 NCR3LG1 PEX12 PRSS23 PTGES RETREG3 RNASEK SLC10A1 SLC10A2 SSMEM1 STX1A TMEM14B TMEM35A TMPRSS2 TMX2 ZDHHC15	26 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		84065	11098
HPRD ID		13167	07149
Ensembl ID		ENSG00000186501	ENSG00000150687
Uniprot IDs		Q9H0R3	O95084
PDB IDs
Enriched GO Terms of Interacting Partners?
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