TMEM222 and SLC10A2

Data Source:
BioGRID (two hybrid)

		TMEM222	SLC10A2
Description		transmembrane protein 222	solute carrier family 10 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process		Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport
Pathways			Recycling of bile acids and salts
Drugs			Volixibat
Diseases			Primary bile acid malabsorption
GWAS		Alanine aminotransferase levels ( 31219225)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) epithelial cell adhesion molecule levels ( 25147954) Esophageal cancer (alcohol interaction) ( 22960999) Gallstone disease ( 30504769) Late-onset Alzheimer's disease ( 27770636) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Response to quetiapine in schizophrenia ( 29503163) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		38 interacting genes: ABHD16A AQP6 BIK BSCL2 CD79A CLDN5 CLRN1 COMT CRB3 CREB3 CREB3L1 EBP ELOVL4 ERG28 ERGIC3 EVI2B FAM174A FAM209A HIBADH HSD17B13 KIR2DL3 LMNA LRRC59 NCR3LG1 PEX12 PRSS23 PTGES RETREG3 RNASEK SLC10A1 SLC10A2 SSMEM1 STX1A TMEM14B TMEM35A TMPRSS2 TMX2 ZDHHC15	10 interacting genes: C3orf52 CCL4L2 CTXN3 EFNA5 IFITM3 NRM PSENEN TEX264 TMEM222 UPK1B
Entrez ID		84065	6555
HPRD ID		13167	03189
Ensembl ID		ENSG00000186501	ENSG00000125255
Uniprot IDs		Q9H0R3	Q12908
PDB IDs
Enriched GO Terms of Interacting Partners?
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