CBX6 and PCGF2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		CBX6	PCGF2
Description		chromobox 6	polycomb group ring finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex	Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Single-stranded RNA Binding Protein Binding	DNA Binding Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Silencing Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of G0 To G1 Transition Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription	SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Plateletcrit ( 32888494)
Interacting Genes		6 interacting genes: HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6	26 interacting genes: ABHD6 CBX2 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA PELI2 PHC1 PHC2 RBCK1 RING1 RNF2 SPDEF STX2 TRAF2 UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7
Entrez ID		23466	7703
HPRD ID		13005	10621
Ensembl ID		ENSG00000183741	ENSG00000277258
Uniprot IDs		B0QXZ6 O95503	A0A024R1V6 P35227
PDB IDs		3GV6 3I90
Enriched GO Terms of Interacting Partners?
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