GET1 and ABHD5

Data Source:
BioGRID (two hybrid)

		GET1	ABHD5
Description		guided entry of tail-anchored proteins factor 1	abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Tail-anchored Membrane Protein Insertion Into ER Membrane	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Triglyceride catabolism
Drugs
Diseases			Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS			General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825)
Interacting Genes		28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42	21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12
Entrez ID		7485	51099
HPRD ID		04224	11986
Ensembl ID		ENSG00000182093	ENSG00000011198
Uniprot IDs		O00258	A0A0S2Z5D6 Q8WTS1
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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