ABHD5 and GET1

Data Source:
BioGRID (two hybrid)

		ABHD5	GET1
Description		abhydrolase domain containing 5, lysophosphatidic acid acyltransferase	guided entry of tail-anchored proteins factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity	Protein Binding
	Biological Process	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis	Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Triglyceride catabolism	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS		General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825)
Interacting Genes		21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12	28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42
Entrez ID		51099	7485
HPRD ID		11986	04224
Ensembl ID		ENSG00000011198	ENSG00000182093
Uniprot IDs		A0A0S2Z5D6 Q8WTS1	O00258
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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