ABHD5 and PLIN2

Data Source:
HPRD (two hybrid, in vitro)

		ABHD5	PLIN2
Description		abhydrolase domain containing 5, lysophosphatidic acid acyltransferase	perilipin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Nucleus Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity	Protein Binding
	Biological Process	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis	Positive Regulation Of Sequestering Of Triglyceride Response To Organic Cyclic Compound Long-chain Fatty Acid Transport Regulation Of Lipid Metabolic Process Lipid Storage Response To Drug
Pathways		Triglyceride catabolism	PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy
Drugs
Diseases		Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS		General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825)	Abdominal aortic calcification levels ( 31659325) Systolic blood pressure ( 30578418)
Interacting Genes		21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12	7 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 POGZ SFT2D2
Entrez ID		51099	123
HPRD ID		11986	00057
Ensembl ID		ENSG00000011198	ENSG00000147872
Uniprot IDs		A0A0S2Z5D6 Q8WTS1	Q6FHZ7 Q99541
PDB IDs
Enriched GO Terms of Interacting Partners?
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