TALDO1 and LSM8

Data Source:
HPRD (two hybrid)

		TALDO1	LSM8
Description		transaldolase 1	LSM8 homolog, U6 small nuclear RNA associated
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GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate Glyceronetransferase Activity Protein Binding Monosaccharide Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Carbohydrate Metabolic Process Xylulose Biosynthetic Process Fructose 6-phosphate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Glyceraldehyde-3-phosphate Metabolic Process Interleukin-12-mediated Signaling Pathway	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways		Insulin effects increased synthesis of Xylulose-5-Phosphate TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P Pentose phosphate pathway Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Proteinuria and chronic kidney disease ( 26420894)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 30108155)
Interacting Genes		7 interacting genes: LSM8 PEA15 TERF1 TERF2 TERF2IP UBE3A ZHX1	49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		6888	51691
HPRD ID		03640	06288
Ensembl ID		ENSG00000177156	ENSG00000128534
Uniprot IDs		A0A140VK56 P37837	A4D0W0 O95777
PDB IDs		1F05	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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