LSM8 and RSC1A1

Data Source:
BioGRID (two hybrid)

		LSM8	RSC1A1
Description		LSM8 homolog, U6 small nuclear RNA associated	regulator of solute carriers 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex	Nucleoplasm Golgi Apparatus Plasma Membrane Cell Junction
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	Protein Binding Sodium Channel Inhibitor Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Glucose Transmembrane Transport Negative Regulation Of Nucleoside Transport Negative Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Exocytosis Negative Regulation Of Transport Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		mRNA Splicing - Major Pathway	Organic cation transport Intestinal hexose absorption
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 30108155)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	3 interacting genes: LSM8 ODC1 RAD23B
Entrez ID		51691	6248
HPRD ID		06288	15994
Ensembl ID		ENSG00000128534	ENSG00000215695
Uniprot IDs		A4D0W0 O95777	Q92681
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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