LSM8 and MRPL48

Data Source:
BioGRID (two hybrid)

		LSM8	MRPL48
Description		LSM8 homolog, U6 small nuclear RNA associated	mitochondrial ribosomal protein L48
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		mRNA Splicing - Major Pathway	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 30108155)	Dimensional psychopathology (Cognitive) ( 29496196) Major depressive disorder ( 29317602) Obesity-related traits ( 23251661)
Interacting Genes		49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	4 interacting genes: APP EXOSC2 LSM8 OXA1L
Entrez ID		51691	51642
HPRD ID		06288	14767
Ensembl ID		ENSG00000128534	ENSG00000175581
Uniprot IDs		A4D0W0 O95777	F5H8D0 Q96GC5
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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