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SYN1 and RB1CC1
Data Source:
BioGRID
(two hybrid)
SYN1
RB1CC1
Description
synapsin I
RB1 inducible coiled-coil 1
Image
No pdb structure
GO Annotations
Cellular Component
Synaptonemal Complex
Golgi Apparatus
Cytosol
Cytoskeleton
Synaptic Vesicle
Postsynaptic Density
Axon
Dendrite
Synaptic Vesicle Membrane
Presynaptic Active Zone
Schaffer Collateral - CA1 Synapse
Extrinsic Component Of Synaptic Vesicle Membrane
Anchored Component Of Synaptic Vesicle Membrane
Phagophore Assembly Site
Autophagosome Membrane
Lysosome
Endoplasmic Reticulum Membrane
Cytosol
Extrinsic Component Of Membrane
Nuclear Membrane
Phagophore Assembly Site Membrane
Atg1/ULK1 Kinase Complex
Molecular Function
Actin Binding
Transporter Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Identical Protein Binding
Calcium-dependent Protein Binding
Protein Binding
Protein Kinase Binding
Molecular Adaptor Activity
Biological Process
Chemical Synaptic Transmission
Neurotransmitter Secretion
Regulation Of Neurotransmitter Secretion
Neuron Development
Synapse Organization
Synaptic Vesicle Clustering
Regulation Of Synaptic Vesicle Cycle
Regulation Of Synaptic Vesicle Exocytosis
Autophagosome Assembly
Autophagy Of Mitochondrion
Liver Development
Positive Regulation Of Protein Phosphorylation
Autophagy
Cell Cycle
Heart Development
Macroautophagy
Regulation Of Macroautophagy
Autophagy Of Peroxisome
Piecemeal Microautophagy Of The Nucleus
Positive Regulation Of Cell Size
Positive Regulation Of JNK Cascade
Reticulophagy
Glycophagy
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Serotonin Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Macroautophagy
Drugs
Adenosine 5'-[gamma-thio]triphosphate
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Body size at age 10 (
32376654
)
Immunoglobulin light chain (AL) amyloidosis (liver involvement) (
28679651
)
Mitochondrial DNA copy number (white blood cells) (
30704525
)
Refractive error (
32231278
)
Waist circumference adjusted for body mass index (
28552196
)
Interacting Genes
30 interacting genes:
AMPH
BIN1
BLM
CAMK1
CAMK2G
CDK5
CRK
ERG
GRB2
ITSN2
KAT5
MAPK3
NOS1
NOS1AP
PAK1
PAK2
PAK3
PFN2
PIK3R1
PLCG1
PRKACA
RASA1
RB1CC1
S100A1
SNCA
SPTAN1
SRC
SYN2
SYN3
VIM
33 interacting genes:
AZI2
BAP1
BLID
COP1
EPSTI1
ERRFI1
EXOC1
GABARAP
GABARAPL1
GABARAPL2
GLCE
GREB1
HBP1
IL13RA2
IL24
ITIH5
LYPD3
MADD
MRC2
NSD3
PSMC3IP
PTK2
PTK2B
RNF20
SYN1
TAX1BP1
TBKBP1
THRSP
UBC
UMPS
VHL
VPS45
WIF1
Entrez ID
6853
9821
HPRD ID
02433
06019
Ensembl ID
ENSG00000008056
ENSG00000023287
Uniprot IDs
P17600
Q8TDY2
PDB IDs
6DCE
6GMA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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