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SRSF1 and C1QBP
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
SRSF1
C1QBP
Description
serine and arginine rich splicing factor 1
complement C1q binding protein
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Exon-exon Junction Complex
Catalytic Step 2 Spliceosome
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Plasma Membrane
Cell Surface
Membrane
Presynaptic Active Zone
Glutamatergic Synapse
GABA-ergic Synapse
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
DNA Topoisomerase Binding
Complement Component C1q Complex Binding
Transcription Corepressor Activity
MRNA Binding
Protein Kinase C Binding
Protein Binding
Hyaluronic Acid Binding
Transcription Factor Binding
Translation Activator Activity
Kininogen Binding
Adrenergic Receptor Binding
Mitochondrial Ribosome Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
MRNA 5'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Splice Site Selection
MRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Negative Regulation Of Transcription By RNA Polymerase II
MRNA Processing
Apoptotic Process
Immune Response
Complement Activation, Classical Pathway
Blood Coagulation, Intrinsic Pathway
RNA Splicing
Phosphatidylinositol 3-kinase Signaling
Viral Process
Regulation Of Complement Activation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-12 Production
Negative Regulation Of MDA-5 Signaling Pathway
Negative Regulation Of RIG-I Signaling Pathway
Mature Ribosome Assembly
Positive Regulation Of Apoptotic Process
Innate Immune Response
Positive Regulation Of Cell Adhesion
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Defense Response To Virus
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Mitochondrial Translation
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Trophoblast Cell Migration
Positive Regulation Of Dendritic Cell Chemotaxis
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Apoptotic factor-mediated response
Intrinsic Pathway of Fibrin Clot Formation
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
Drugs
Copper
Hyaluronic acid
Copper
Diseases
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
43 interacting genes:
AKAP17A
APP
BCL10
C1QBP
CACNA1A
CD8A
CDC42
CDK12
CDK6
CLK1
DIDO1
DYRK1A
GEMIN2
HIPK3
HNRNPA0
LNX1
LUC7L3
NFYA
NXF1
PPARG
PRPF4
PRPF4B
PSIP1
RNPS1
SCAF11
SNRNP70
SREK1
SRPK1
SRPK2
SRSF10
SRSF11
SRSF4
SRSF5
TCERG1
TNPO3
TOP1
TP53
TRA2B
U2AF1
U2AF2
XBP1
YTHDC1
ZRSR2
99 interacting genes:
C1QA
CEBPA
COIL
DUX4
EXOSC6
GAB1
GABRB1
HABP4
HMGB1
HMGB2
HNRNPD
HRK
KLF1
MAPK1
MAPK3
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MMP14
NFKBIE
NFYB
PRKCA
PRKCD
PRKCZ
PRKD1
PRRC2A
SRSF1
SRSF9
TOP3B
YWHAB
YWHAG
Entrez ID
6426
708
HPRD ID
02887
03168
Ensembl ID
ENSG00000136450
ENSG00000108561
Uniprot IDs
Q07955
Q59FA2
Q07021
PDB IDs
1X4A
2M7S
2M8D
2O3D
3BEG
4C0O
1P32
3RPX
6SZW
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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