Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SRSF1 and XBP1
Data Source:
BioGRID
(two hybrid)
SRSF1
XBP1
Description
serine and arginine rich splicing factor 1
X-box binding protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Exon-exon Junction Complex
Catalytic Step 2 Spliceosome
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
DNA Topoisomerase Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
MRNA 5'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Splice Site Selection
MRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Angiogenesis
Liver Development
Positive Regulation Of Immunoglobulin Production
Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Fatty Acid Biosynthetic Process
Autophagy
Apoptotic Process
Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Muscle Organ Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Myotube Differentiation
Protein Transport
Positive Regulation Of Cell Migration
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Nutrient
Positive Regulation Of Interleukin-6 Production
Cellular Response To Insulin Stimulus
Cellular Triglyceride Homeostasis
Positive Regulation Of Vascular Wound Healing
IRE1-mediated Unfolded Protein Response
ATF6-mediated Unfolded Protein Response
Cellular Response To Glucose Starvation
Cholesterol Homeostasis
Negative Regulation Of Apoptotic Process
Positive Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Neuron Development
Fatty Acid Homeostasis
Sterol Homeostasis
Adipose Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Fructose Stimulus
Cellular Response To Glucose Stimulus
Cellular Response To Interleukin-4
Cellular Response To Peptide Hormone Stimulus
Positive Regulation Of Plasma Cell Differentiation
Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Lactation
Response To Insulin-like Growth Factor Stimulus
Positive Regulation Of Hepatocyte Proliferation
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Drugs
Copper
Diseases
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Esophageal cancer (squamous cell) (
22960999
)
Esophageal squamous cell carcinoma (
25129146
)
Heel bone mineral density (
28869591
)
Mean arterial pressure (
29403010
)
Pancreatic cancer (
25086665
)
Interacting Genes
43 interacting genes:
AKAP17A
APP
BCL10
C1QBP
CACNA1A
CD8A
CDC42
CDK12
CDK6
CLK1
DIDO1
DYRK1A
GEMIN2
HIPK3
HNRNPA0
LNX1
LUC7L3
NFYA
NXF1
PPARG
PRPF4
PRPF4B
PSIP1
RNPS1
SCAF11
SNRNP70
SREK1
SRPK1
SRPK2
SRSF10
SRSF11
SRSF4
SRSF5
TCERG1
TNPO3
TOP1
TP53
TRA2B
U2AF1
U2AF2
XBP1
YTHDC1
ZRSR2
22 interacting genes:
ATF6
ATF6B
CREBZF
ESR1
FOS
FUBP3
GLI1
H1-0
H1-10
HDGF
MDM2
MTNR1B
NR0B2
PCBD2
RBL2
SRSF1
SSX4
TRIP4
UBE2I
UBE2V1
ZNF440
ZNF580
Entrez ID
6426
7494
HPRD ID
02887
01908
Ensembl ID
ENSG00000136450
ENSG00000100219
Uniprot IDs
Q07955
Q59FA2
A0A024R1F0
P17861
PDB IDs
1X4A
2M7S
2M8D
2O3D
3BEG
4C0O
6R5Q
6R6G
6R6P
6R7Q
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?