KLHL12 and RIN1

Data Source:
BioGRID (two hybrid)

		KLHL12	RIN1
Description		kelch like family member 12	Ras and Rab interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Protein Monoubiquitination Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Degradation of DVL	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972 31043756)
Interacting Genes		62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL1 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4	50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1
Entrez ID		59349	9610
HPRD ID		13925	05813
Ensembl ID		ENSG00000117153	ENSG00000174791
Uniprot IDs		Q53G59 Q9H7R2	A0A0S2Z4U0 Q13671
PDB IDs		2VPJ 6TTK 6V7O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?