RIN1 and RALGDS

Data Source:
BioGRID (two hybrid)

		RIN1	RALGDS
Description		Ras and Rab interactor 1	ral guanine nucleotide dissociation stimulator
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Nucleus Cytosol Brush Border
	Molecular Function	GTPase Activator Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity
	Biological Process	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity	Ras Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		RAB GEFs exchange GTP for GDP on RABs	p38MAPK events p38MAPK events RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1	26 interacting genes: AFDN ARRB1 ARRB2 CD68 CNKSR1 CYSRT1 HOXA1 HRAS KRAS KRTAP10-8 LRPAP1 MAPK3 MRAS NF2 PDPK1 RAP1A RAP1B RAP1GAP RAP2A RAP2B RAPGEF2 RIN1 RIT1 RIT2 RRAS RRAS2
Entrez ID		9610	5900
HPRD ID		05813	03371
Ensembl ID		ENSG00000174791	ENSG00000160271
Uniprot IDs		A0A0S2Z4U0 Q13671	Q12967 Q8N4Y1
PDB IDs			1RAX 2B3A 2RGF 3KH0
Enriched GO Terms of Interacting Partners?
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