RIN1 and SEC23B

Data Source:
BioGRID (two hybrid)

		RIN1	SEC23B
Description		Ras and Rab interactor 1	SEC23 homolog B, COPII coat complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	GTPase Activator Activity Protein Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity	Intracellular Protein Transport Positive Regulation Of GTPase Activity COPII-coated Vesicle Cargo Loading
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Bipolar disorder ( 21926972 31043756)	Refractive error ( 32231278)
Interacting Genes		50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1	25 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 RIN1 SEC23A SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UGT1A1
Entrez ID		9610	10483
HPRD ID		05813	11543
Ensembl ID		ENSG00000174791	ENSG00000101310
Uniprot IDs		A0A0S2Z4U0 Q13671	A0A2R8YFH5 Q15437
PDB IDs
Enriched GO Terms of Interacting Partners?
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