KLHL12 and KLHL24

Data Source:
BioGRID (two hybrid)

		KLHL12	KLHL24
Description		kelch like family member 12	kelch like family member 24
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Cytoplasm Adherens Junction Desmosome Axon Cul3-RING Ubiquitin Ligase Complex Perikaryon
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Monoubiquitination Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Protein Ubiquitination Intermediate Filament Organization Protein Autoubiquitination Regulation Of Kainate Selective Glutamate Receptor Activity
Pathways		Degradation of DVL
Drugs
Diseases
GWAS			Birth weight ( 31043758) Periventricular white matter hyperintensities ( 32517579) White matter hyperintensities ( 32358547)
Interacting Genes		62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL1 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4	3 interacting genes: ATP6V1C2 KLHL12 NCK2
Entrez ID		59349	54800
HPRD ID		13925	16838
Ensembl ID		ENSG00000117153	ENSG00000114796
Uniprot IDs		Q53G59 Q9H7R2	Q6TFL4
PDB IDs		2VPJ 6TTK 6V7O
Enriched GO Terms of Interacting Partners?
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