RIN1 and CAPNS2

Data Source:
BioGRID (two hybrid)

		RIN1	CAPNS2
Description		Ras and Rab interactor 1	calpain small subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity	Proteolysis Extracellular Matrix Disassembly
Pathways		RAB GEFs exchange GTP for GDP on RABs	Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Thyroid hormone levels ( 23408906)
Interacting Genes		50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1	9 interacting genes: APP ARMC10 CAPN2 CMTM5 OXNAD1 PHACTR3 PPIC PRPF31 RIN1
Entrez ID		9610	84290
HPRD ID		05813	16682
Ensembl ID		ENSG00000174791	ENSG00000256812
Uniprot IDs		A0A0S2Z4U0 Q13671	Q96L46
PDB IDs
Enriched GO Terms of Interacting Partners?
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