Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SMCO4 and PTGES
Data Source:
BioGRID
(two hybrid)
SMCO4
PTGES
Description
single-pass membrane protein with coiled-coil domains 4
prostaglandin E synthase
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Integral Component Of Membrane
Nuclear Envelope Lumen
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Molecular_function
Protein Binding
Glutathione Transferase Activity
Glutathione Peroxidase Activity
Prostaglandin-D Synthase Activity
Protein Binding
Glutathione Binding
Prostaglandin-E Synthase Activity
Biological Process
Biological_process
Prostaglandin Biosynthetic Process
Acute Inflammatory Response
Chronic Inflammatory Response
Prostaglandin Metabolic Process
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Response To Organic Cyclic Compound
Sensory Perception Of Pain
Cyclooxygenase Pathway
Regulation Of Fever Generation
Positive Regulation Of Prostaglandin Secretion
Response To Lipopolysaccharide
Response To Retinoic Acid
Response To Cytokine
Regulation Of Inflammatory Response
Response To Calcium Ion
Cellular Oxidant Detoxification
Pathways
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Insulin levels in response to oral glucose tolerance test (30 minutes) (
29093273
)
Asthma (
27611488
)
Pars orbitalis volume (
31530798
)
Interacting Genes
59 interacting genes:
AQP6
BNIP3L
CD79A
CLEC10A
CLTRN
CPLX4
CREB3L1
CXCR2
EBP
ERGIC3
FAM174A
FAM209A
FAM210B
FFAR2
GJA8
GKN1
GPA33
GPR152
GPR42
HHLA2
ICAM3
IL10RA
KASH5
KCNK5
KIR3DL1
KRT40
KRTAP10-3
KRTAP10-7
LEPROTL1
LMNA
LRRC25
M6PR
MGST3
MS4A3
MUC1
PEX12
PLD3
PTGES
RETREG3
SCN3B
SLC16A2
SLC18A1
SLC35C2
SLC41A3
SLC7A1
SLC7A14
SMIM3
SPINT1
STOM
SUSD3
SYNE4
SYNPR
TEX29
TFEC
TMEM139
TMEM80
TMX2
VSIR
WBP1
18 interacting genes:
BET1
C4orf3
EHHADH
GIMAP1
GIMAP5
PLP2
PTGER1
PTGER2
SEC22A
SERP2
SMCO4
TMEM19
TMEM222
TMEM65
VAMP3
VAMP4
VAPB
YIF1A
Entrez ID
56935
9536
HPRD ID
17008
05528
Ensembl ID
ENSG00000166002
ENSG00000148344
Uniprot IDs
A0A024R3A3
Q9NRQ5
O14684
PDB IDs
3DWW
4AL0
4AL1
4BPM
4WAB
4YK5
4YL0
4YL1
4YL3
5BQG
5BQH
5BQI
5K0I
5T36
5T37
5TL9
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?