PTGES and GIMAP1

Data Source:
BioGRID (two hybrid)

		PTGES	GIMAP1
Description		prostaglandin E synthase	GTPase, IMAP family member 1
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GO Annotations	Cellular Component	Nuclear Envelope Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Prostaglandin-D Synthase Activity Protein Binding Glutathione Binding Prostaglandin-E Synthase Activity	Protein Binding GTP Binding
	Biological Process	Prostaglandin Biosynthetic Process Acute Inflammatory Response Chronic Inflammatory Response Prostaglandin Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Organic Cyclic Compound Sensory Perception Of Pain Cyclooxygenase Pathway Regulation Of Fever Generation Positive Regulation Of Prostaglandin Secretion Response To Lipopolysaccharide Response To Retinoic Acid Response To Cytokine Regulation Of Inflammatory Response Response To Calcium Ion Cellular Oxidant Detoxification
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Asthma ( 27611488) Pars orbitalis volume ( 31530798)
Interacting Genes		18 interacting genes: BET1 C4orf3 EHHADH GIMAP1 GIMAP5 PLP2 PTGER1 PTGER2 SEC22A SERP2 SMCO4 TMEM19 TMEM222 TMEM65 VAMP3 VAMP4 VAPB YIF1A	39 interacting genes: AQP6 ARL13B BLCAP CD79A CLEC10A CPLX4 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCGR2A GJA8 HSD17B11 IL3RA JAGN1 MFSD14B MGST3 PTGES REEP4 RMDN3 SCN3B SLC10A6 SLC14A1 SLC18A1 STOM STX1A THAP4 TM4SF19 TMEM101 TMEM14B TMEM35A TMEM45B TMEM79 TMX1 TMX2 ZDHHC15 ZFYVE27
Entrez ID		9536	170575
HPRD ID		05528	16278
Ensembl ID		ENSG00000148344	ENSG00000213203
Uniprot IDs		O14684	A0A090N8Z4 Q8WWP7
PDB IDs		3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9	3V70
Enriched GO Terms of Interacting Partners?
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