SMCO4 and MS4A3

Data Source:
BioGRID (two hybrid)

		SMCO4	MS4A3
Description		single-pass membrane protein with coiled-coil domains 4	membrane spanning 4-domains A3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Neutrophil Degranulation Regulation Of Cell Cycle
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273)	Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)
Interacting Genes		59 interacting genes: AQP6 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1
Entrez ID		56935	932
HPRD ID		17008	09403
Ensembl ID		ENSG00000166002	ENSG00000149516
Uniprot IDs		A0A024R3A3 Q9NRQ5	Q96HJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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