PTGES and TMEM19

Data Source:
BioGRID (two hybrid)

		PTGES	TMEM19
Description		prostaglandin E synthase	transmembrane protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Membrane Integral Component Of Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Prostaglandin-D Synthase Activity Protein Binding Glutathione Binding Prostaglandin-E Synthase Activity	Protein Binding
	Biological Process	Prostaglandin Biosynthetic Process Acute Inflammatory Response Chronic Inflammatory Response Prostaglandin Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Organic Cyclic Compound Sensory Perception Of Pain Cyclooxygenase Pathway Regulation Of Fever Generation Positive Regulation Of Prostaglandin Secretion Response To Lipopolysaccharide Response To Retinoic Acid Response To Cytokine Regulation Of Inflammatory Response Response To Calcium Ion Cellular Oxidant Detoxification
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Asthma ( 27611488) Pars orbitalis volume ( 31530798)	Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		18 interacting genes: BET1 C4orf3 EHHADH GIMAP1 GIMAP5 PLP2 PTGER1 PTGER2 SEC22A SERP2 SMCO4 TMEM19 TMEM222 TMEM65 VAMP3 VAMP4 VAPB YIF1A	38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LEPROTL1 LY6E MC4R MFSD14B PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM159 TMEM45A
Entrez ID		9536	55266
HPRD ID		05528	15530
Ensembl ID		ENSG00000148344	ENSG00000139291
Uniprot IDs		O14684	A0A024RBA1 Q96HH6
PDB IDs		3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9
Enriched GO Terms of Interacting Partners?
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