DMAP1 and EXOC8

Data Source:
BioGRID (two hybrid)

		DMAP1	EXOC8
Description		DNA methyltransferase 1 associated protein 1	exocyst complex component 8
Image			No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Corepressor Activity Protein Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization
Pathways		HATs acetylate histones	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Hemoglobin concentration ( 27863252)
Interacting Genes		38 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1	88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4
Entrez ID		55929	149371
HPRD ID		05465	09943
Ensembl ID		ENSG00000178028	ENSG00000116903
Uniprot IDs		Q9NPF5	Q8IYI6
PDB IDs		3HM5 4IEJ
Enriched GO Terms of Interacting Partners?
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