DMAP1 and GAS8

Data Source:
BioGRID (two hybrid)

		DMAP1	GAS8
Description		DNA methyltransferase 1 associated protein 1	growth arrest specific 8
Image			No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex	Golgi Apparatus Cytosol Microtubule Plasma Membrane Cilium Axoneme Motile Cilium Ciliary Basal Body
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Corepressor Activity Protein Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Cellular Protein Localization Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium Regulation Of Microtubule Binding
Pathways		HATs acetylate histones	Activation of SMO
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		38 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1	111 interacting genes: ARL6IP1 BCAR3 BHLHB9 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 KRT27 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792
Entrez ID		55929	2622
HPRD ID		05465	05533
Ensembl ID		ENSG00000178028	ENSG00000141013
Uniprot IDs		Q9NPF5	A0A087WZT7 A0A384MR00 B7Z1U9 O95995
PDB IDs		3HM5 4IEJ
Enriched GO Terms of Interacting Partners?
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