DMAP1 and SUOX

Data Source:
BioGRID (two hybrid)

		DMAP1	SUOX
Description		DNA methyltransferase 1 associated protein 1	sulfite oxidase
Image
GO Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Corepressor Activity Protein Binding	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated	Sulfur Compound Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase
Pathways		HATs acetylate histones	Sulfide oxidation to sulfate
Drugs			{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Metabolite levels ( 23823483)	Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)
Interacting Genes		38 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1	77 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC
Entrez ID		55929	6821
HPRD ID		05465	06055
Ensembl ID		ENSG00000178028	ENSG00000139531
Uniprot IDs		Q9NPF5	A0A024RB79 P51687
PDB IDs		3HM5 4IEJ	1MJ4
Enriched GO Terms of Interacting Partners?
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