EXOC8 and SYT17

Data Source:
BioGRID (two hybrid)

		EXOC8	SYT17
Description		exocyst complex component 8	synaptotagmin 17
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm	Plasma Membrane Exocytic Vesicle
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)	Alcohol dependence ( 21876473) Fruit consumption ( 32066663) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4	50 interacting genes: AK8 APP APTX BLZF1 CBY2 CCDC102B CCDC33 CCDC85B CCNB1IP1 CEP63 CEP70 CHMP4A COG6 DEPDC5 EXOC8 FAM9B FRMD6 GMCL1 GOLGA2 GOLGA6A HIP1 HOOK2 IKZF1 LSM7 LZTS1 LZTS2 MAD1L1 MAJIN MCC MEOX1 MEOX2 MID2 NIF3L1 NINL PFDN5 PIBF1 PICK1 POF1B RUNDC3A SDCBP2 SNRNP35 SSX2IP TRAF2 TRIM27 TSC22D4 TSNAX VPS9D1 ZNF438 ZNF597 ZRANB1
Entrez ID		149371	51760
HPRD ID		09943	17425
Ensembl ID		ENSG00000116903	ENSG00000103528
Uniprot IDs		Q8IYI6	H3BN78 H3BRH9 Q9BSW7
PDB IDs			2ENP
Enriched GO Terms of Interacting Partners?
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