EXOC8 and RAB3IL1

Data Source:
BioGRID (two hybrid)

		EXOC8	RAB3IL1
Description		exocyst complex component 8	RAB3A interacting protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm	Cytosol Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization	Exocytosis Protein Transport Regulation Of Catalytic Activity
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)	Metabolite levels ( 23823483) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4	27 interacting genes: C14orf119 C2orf68 CCDC57 COG6 CTDSP1 CYSRT1 EXOC8 FHL5 HSF2BP IP6K1 KRT34 KRT40 KRTAP6-3 MAP3K1 MTUS2 NBPF19 NOTCH2NLA NUDT18 PSMA3 RAB11A RAB3A RAB3IP RAB8A SATB2 STX1A TIGD7 TTC7B
Entrez ID		149371	5866
HPRD ID		09943	10181
Ensembl ID		ENSG00000116903	ENSG00000167994
Uniprot IDs		Q8IYI6	Q8TBN0
PDB IDs			4LI0
Enriched GO Terms of Interacting Partners?
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