GDAP1 and CLCN7

Data Source:
BioGRID (two hybrid)

		GDAP1	CLCN7
Description		ganglioside induced differentiation associated protein 1	chloride voltage-gated channel 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Membrane Integral Component Of Mitochondrial Outer Membrane	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Mitochondrial Fission Protein Targeting To Mitochondrion Glutathione Metabolic Process Mitochondrial Fusion	Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Class I peroxisomal membrane protein import	Stimuli-sensing channels
Drugs
Diseases			Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Dysmenorrheic pain ( 27454463) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 32499647) Waist circumference ( 17903300)	Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: ABHD16A APOD CLCN7 DCBLD2 FAM114A1 PNLIPRP1 STARD4 TMEM14B TMEM218 TUBB	17 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LMNA LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B
Entrez ID		54332	1186
HPRD ID		05963	04103
Ensembl ID		ENSG00000104381	ENSG00000103249
Uniprot IDs		Q8TB36	P51798
PDB IDs			7BXU 7JM7
Enriched GO Terms of Interacting Partners?
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