DCUN1D1 and UBE2F

Data Source:
BioGRID (pull down, pull down)

		DCUN1D1	UBE2F
Description		defective in cullin neddylation 1 domain containing 1	ubiquitin conjugating enzyme E2 F (putative)
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytosol
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding ATP Binding NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity
	Biological Process	Regulation Of Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation	Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation
Pathways		Neddylation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)	Lean body mass ( 28552196)
Interacting Genes		33 interacting genes: ABRAXAS2 ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CDIP1 CUL5 DAZAP2 DVL2 FAM168A GMPPA LAPTM5 LZTS2 MAP3K1 NEDD4 PLEKHB2 RHOA RNF11 SMAD2 SUSD6 TLE5 TMEM239 TP53BP2 TRIM39 TRIM54 TRIM8 UBC UBE2D3 UBE2F UBE2M VPS37B	12 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RC3H1 RNF34 RNF7 UBA3
Entrez ID		54165	140739
HPRD ID		12067	14812
Ensembl ID		ENSG00000043093	ENSG00000184182
Uniprot IDs		B4DM76 C9JVE2 Q96GG9	Q969M7
PDB IDs		3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W	2EDI 3FN1 4GBA
Enriched GO Terms of Interacting Partners?
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