DCUN1D1 and FAM168A

Data Source:
BioGRID (two hybrid)

		DCUN1D1	FAM168A
Description		defective in cullin neddylation 1 domain containing 1	family with sequence similarity 168 member A
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding
	Biological Process	Regulation Of Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation	Positive Regulation Of Base-excision Repair
Pathways		Neddylation
Drugs
Diseases
GWAS		Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30061609) Platelet count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		33 interacting genes: ABRAXAS2 ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CDIP1 CUL5 DAZAP2 DVL2 FAM168A GMPPA LAPTM5 LZTS2 MAP3K1 NEDD4 PLEKHB2 RHOA RNF11 SMAD2 SUSD6 TLE5 TMEM239 TP53BP2 TRIM39 TRIM54 TRIM8 UBC UBE2D3 UBE2F UBE2M VPS37B	75 interacting genes: ALKBH4 ATXN1 ATXN1L BOLL C10orf55 C1orf94 CALCOCO2 CAMK2A DAB1 DAZAP2 DCUN1D1 DTX2 EPN2 EPN3 FAM168B FBXW5 HGS HIP1 HR KLHL42 KRTAP19-1 KRTAP19-5 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 MEIS2 NAF1 NFYC OTUB2 OTULIN PATZ1 PEF1 PITX1 PLEKHB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSORS1C1 R3HDM2 RBFOX1 RBPMS RBPMS2 RHOXF2 RNF216 RPS27A SECISBP2 SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TFAP2D TFG TIAL1 TNIP1 TNK1 TOLLIP UBA52 UBAC1 UBASH3B UBC UBE2V1 UBQLN2 UBXN6 UBXN7 VPS37C YOD1 YTHDF1
Entrez ID		54165	23201
HPRD ID		12067	13792
Ensembl ID		ENSG00000043093	ENSG00000054965
Uniprot IDs		B4DM76 C9JVE2 Q96GG9	Q92567
PDB IDs		3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W
Enriched GO Terms of Interacting Partners?
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