UBE2F and DCUN1D1

Data Source:
BioGRID (pull down, pull down)

		UBE2F	DCUN1D1
Description		ubiquitin conjugating enzyme E2 F (putative)	defective in cullin neddylation 1 domain containing 1
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GO Annotations	Cellular Component	Nucleus Cytosol	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Binding NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation	Regulation Of Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Neddylation
Drugs
Diseases
GWAS		Lean body mass ( 28552196)	Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)
Interacting Genes		12 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RC3H1 RNF34 RNF7 UBA3	33 interacting genes: ABRAXAS2 ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CDIP1 CUL5 DAZAP2 DVL2 FAM168A GMPPA LAPTM5 LZTS2 MAP3K1 NEDD4 PLEKHB2 RHOA RNF11 SMAD2 SUSD6 TLE5 TMEM239 TP53BP2 TRIM39 TRIM54 TRIM8 UBC UBE2D3 UBE2F UBE2M VPS37B
Entrez ID		140739	54165
HPRD ID		14812	12067
Ensembl ID		ENSG00000184182	ENSG00000043093
Uniprot IDs		Q969M7	B4DM76 C9JVE2 Q96GG9
PDB IDs		2EDI 3FN1 4GBA	3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W
Enriched GO Terms of Interacting Partners?
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